Dual receptor T cells mediate effective antitumor immune responses via increased recognition of tumor antigens.

Hyun J JangChristine CaronCalvin K LeeLu WangBurhan JamaJack D Bui Gerald P Morris

Published in: Journal for immunotherapy of cancer (2023)

These results discover an unrecognized role for dual TCR cells in protective immune function and identify these cells and their TCRs as a potential resource for antitumor immunotherapy.

Keyphrases

induced apoptosis
cell cycle arrest
immune response
dendritic cells
endoplasmic reticulum stress
toll like receptor
climate change
oxidative stress
regulatory t cells
inflammatory response
human health