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Cytological diagnosis of olfactory neuroblastoma at metastatic sites, with emphasis on role of insulinoma-associated protein 1 immunocytochemistry.

Diya RoySanjay SriramAanchal KakkarRajeev KumarKavneet KaurDeepali JainAtul SharmaAlok Thakar
Published in: Diagnostic cytopathology (2022)
Metatstatic ONB can resemble other small round cell tumors, as all the diagnostic features of ONB may not be readily evident. INSM1 immunocytochemistry has high sensitivity and specificity and can reliably be used as a single marker to support the cytomorphology for a confirmatory diagnosis of ONB, even on direct smears if a cell block is not available.
Keyphrases
  • single cell
  • cell therapy
  • small cell lung cancer
  • stem cells
  • mesenchymal stem cells
  • structural basis
  • fine needle aspiration