BRCA1 and BRCA2 gene variants and nonsyndromic cleft lip/palate.
Nicholas RodriguezLorena MailiBrett T ChiquetSusan H BlantonJacqueline T HechtAriadne LetraPublished in: Birth defects research (2018)
Our results suggest a modest association between BRCA1 and BRCA2 and NSCL/P. Further studies in additional populations and functional studies are needed to elucidate the role of these genes in developmental processes and signaling pathways contributing to NSCL/P.