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Contribution of Necroptosis to Myofiber Death in Idiopathic Inflammatory Myopathies.

Qing-Lin PengYa-Mei ZhangYan-Chun LiuLin LiangWen-Li LiXiao-Lan TianLu ZhangHong-Xia YangXin LuGuo-Chun Wang
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
These findings demonstrate that overactivated necroptosis contributes to muscle damage in IIMs and suggest that necroptosis inhibitors could represent a new therapeutic target in the treatment of IIMs.
Keyphrases
  • oxidative stress
  • skeletal muscle
  • combination therapy