Prediagnostic Serum Vitamin D, Vitamin D Binding Protein Isoforms, and Cancer Survival.
Stephanie J WeinsteinAlison M MondulTracy M LayneKai YuJiaqi HuangRachael Z Stolzenberg-SolomonRegina G ZieglerMark P PurdueWen-Yi HuangChristian C AbnetNeal D FreedmanDemetrius AlbanesPublished in: JNCI cancer spectrum (2022)
Higher circulating 25(OH)D was associated with improved overall and lung cancer survival. As this was especially evident among cases with the genetically determined Gc2 isoform of vitamin D binding protein, such individuals may gain a cancer survival advantage by maintaining higher 25(OH)D blood concentrations.