Alcoholic Acute Pancreatitis, a Retrospective Study about Clinical Risk Factors and Outcomes-A Seven-Year Experience of a Large Tertiary Center.
Deniz GűnșahinAndrei Vicențiu EduMihai Radu PahomeanuTudor Ștefan MituAndreea Irina GhițăAnamaria Simona OdorogCarmen Monica PredaLucian NegreanuPublished in: Biomedicines (2024)
(1) Background: Alcohol consumption is one of the main causes of acute pancreatitis. (2) Material and Methods: In this unicentric retrospective cohort study, we selected 1855 patients from the Bucharest Acute Pancreatitis Index (BUC-API) who presented with acute pancreatitis. We investigated correlations between Alcoholic Acute Pancreatitis (AAP) and the rate of complications, cost, length of hospitalization and rate of recurrence. (3) Results: We found a moderately strong association between AAP and recurrence ( p < 0.01) and observed that the disease is likelier to evolve with pseudocysts and walled-off necrosis than other forms of AP. Patients with AAP are less likely to have a morphologically normal pancreas than patients suffering from AP of other causes ( p < 0.01), but a low probability of requiring intensive care unit admission ( p < 0.01) significantly lowers daily cost (Md = 154.7 EUR compared to Md = 204.4 EUR) ( p < 0.01). (4) Conclusions: This study's data show that patients with AAP have a greater rate of pseudocyst occurrence, lower intensive care unit admittance rate and lower cost of hospitalization than patients with AP of other causes. Typical Sketch: A middle-aged male tobacco smoker with recurrent AP, lower risk of in-hospital mortality and complications such as pseudocysts; treated in a gastroenterological ward and discharged at-will.
Keyphrases
- emergency department
- intensive care unit
- end stage renal disease
- risk factors
- newly diagnosed
- transcription factor
- chronic kidney disease
- ejection fraction
- middle aged
- peritoneal dialysis
- prognostic factors
- machine learning
- patient reported outcomes
- liver injury
- metabolic syndrome
- insulin resistance
- type diabetes
- mass spectrometry
- physical activity
- molecular dynamics
- drug induced
- artificial intelligence
- skeletal muscle
- free survival
- high speed