The rs4430796 SNP of the HNF1β gene associates with type 2 diabetes in older adults.

Wilcelly Machado-SilvaAudrey C Tonet-FuriosoLucy GomesCláudio CórdovaClayton Franco MoraesOtávio Toledo Nóbrega

Published in: Revista da Associacao Medica Brasileira (1992) (2019)

Our results corroborate the possible protective property of the GG genotype from the rs4430796 variation (already presented in the literature) against occurrence of diabetes mellitus, which appears applicable to elderly individuals as well, even in the context of multiple metabolic disorders so typical in older Brazilians.

Keyphrases

community dwelling
genome wide
middle aged
physical activity
systematic review
risk assessment
copy number
dna methylation
nuclear factor
type diabetes
glycemic control
adipose tissue
weight loss