Integrated Transcriptomics and Proteomics Identified CMPK1 as a Potential Biomarker for Type 2 Diabetes Mellitus.

Kang ZhaoRui MaoWei YiZhengyun Ren Yanjun LiuHuawu YangSenlin WangZhonghui Feng

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2024)

Our study showed CMPK1 was upregulated in the liver of T2DM patients and provides a possible new target for screening and diagnosing T2DM in patients with obese and a novel theoretical basis for the pathophysiological mechanism of obesity-related metabolic diseases.

Keyphrases

metabolic syndrome
end stage renal disease
weight loss
type diabetes
glycemic control
ejection fraction
newly diagnosed
chronic kidney disease
insulin resistance
prognostic factors
mass spectrometry
single cell
weight gain
body mass index
physical activity
obese patients
cardiovascular risk factors