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A Glycemic Threshold Above Which the Improvement of β-Cell Function and Glycemia in Response to Insulin Therapy Is Amplified in Early Type 2 Diabetes: The Reversal of Glucotoxicity.

Chang YeJiajie PuChang YeAlexandra EmeryStewart B HarrisSonja M ReichertUlagamadesan VenkatesanNatalia McInnesCaroline Kaercher KramerBernard Zinman
Published in: Diabetes care (2024)
The respective improvements in β-cell function and glycemia in response to short-term IIT are amplified in those in whom baseline fasting glucose exceeds a defined threshold, consistent with reversal of glucotoxicity.
Keyphrases
  • type diabetes
  • glycemic control
  • blood glucose
  • insulin resistance
  • cardiovascular disease
  • blood pressure
  • bone marrow
  • cell therapy
  • smoking cessation