Whole body proton irradiation causes acute damage to bone marrow hematopoietic progenitor and stem cells in mice.
Jianhui ChangYingying WangRupak PathakVijayalakshmi SridharanTamako JonesXiao Wen MaoGregory NelsonMarjan BoermaMartin Hauer-JensenDaohong ZhouLijian ShaoPublished in: International journal of radiation biology (2017)
Exposure to proton-TBI can induce acute damage to BM progenitors and LSK cells.
Keyphrases
- bone marrow
- liver failure
- stem cells
- respiratory failure
- oxidative stress
- induced apoptosis
- drug induced
- traumatic brain injury
- aortic dissection
- mesenchymal stem cells
- cell cycle arrest
- type diabetes
- metabolic syndrome
- signaling pathway
- radiation induced
- acute respiratory distress syndrome
- electron transfer
- severe traumatic brain injury
- wild type
- cell fate