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Metabolic Profiling of Obesity With and Without the Metabolic Syndrome: A Multisample Evaluation.

Lars LindSamira SalihovicJohan SundströmSölve ElmståhlUlf HammarKoen DekkersJohan ÄrnlövJ Gustav SmithGunnar EngströmTove Fall
Published in: The Journal of clinical endocrinology and metabolism (2022)
Our data suggest a graded derangement of the circulating metabolite profile from lean to obese to MetS, in particular for metabolites involved in amino acid synthesis/metabolism and sphingolipid metabolism. Insulin resistance is a plausible mediator of this gradual metabolic deterioration.
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