Alteplase Dose Assessment for Pleural infection Therapy (ADAPT) Study-2: Use of 2.5 mg alteplase as a starting intrapleural dose.
Natalia PopowiczHugh IpEstee P M LauFrancesco PiccoloKirstie DootsonCindy YeohWint Ywe PhuRebecca BrownAlex WestLiju AhmedYun Chor Gary LeePublished in: Respirology (Carlton, Vic.) (2022)
A starting intrapleural regime of 2.5 mg tPA/5 mg DNase, with up-titration if needed, can be effective and deserves further exploration.