Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study.

Julia Hippisley-CoxMartina PatoneXue W MeiDefne SaatciSharon DixonKamlesh KhuntiFrancesco ZaccardiPeter WatkinsonManu Shankar-HariJames DoidgeDavid A HarrisonSimon J GriffinAziz SheikhCarol A C Coupland

Published in: BMJ (Clinical research ed.) (2021)

Increased risks of haematological and vascular events that led to hospital admission or death were observed for short time intervals after first doses of the ChAdOx1 nCoV-19 and BNT162b2 mRNA vaccines. The risks of most of these events were substantially higher and more prolonged after SARS-CoV-2 infection than after vaccination in the same population.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
human health
emergency department
healthcare
risk assessment
binding protein
acute care
adverse drug