Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology.
Elio AdibAmin H NassarSarah Abou AlaiwiStefan GrohaElie W AklLynette M ShollKesi S MichaelMark M AwadPasi A JӓnneAlexander GusevDavid J KwiatkowskiPublished in: Genome medicine (2022)
Among patients with NSCLC, there was significant variability in the prevalence of targetable genomic alterations according to genetic ancestry, histology, and smoking. Patients with LUSC and LCLC have 5% rates of targetable alterations supporting consideration for sequencing in those subtypes.