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Screening for monoclonal B-lymphocyte expansion in a hospital-based Chinese population with lymphocytosis: an observational cohort study.

Jiadai XuJing LiZheng WeiYue WangPeng Liu
Published in: BMJ open (2020)
In Chinese patients with lymphocytosis, there was a relatively high proportion of patients with CLL among individuals over 60 years of age. MBL is an age-related disorder. Non-CLL-like MBL was the most common MBL subtype, almost all of whom displayed a pattern of 'marginal zone lymphoma (MZL)-like' MBL. Lymphocytosis screening among the elderly would be effective in the detection of B-LPD and MBL.
Keyphrases
  • chronic lymphocytic leukemia
  • diffuse large b cell lymphoma
  • middle aged
  • multiple myeloma
  • loop mediated isothermal amplification
  • real time pcr