Tanshinone IIA Alleviates Traumatic Brain Injury by Reducing Ischemia‒Reperfusion via the miR-124-5p/FoxO1 Axis.
Wenbing SuMeifen LvDayu WangYinghong HeHui HanYu ZhangXiuying ZhangShaokun LvLiqing YaoPublished in: Mediators of inflammation (2024)
Tanshinone IIA alleviates ischemic-reperfusion brain injury by inhibiting neuroinflammation through the miR-124-5p/FoxO1 axis. This finding provides a theoretical basis for mechanistic research on cerebral ischemia-reperfusion injury.
Keyphrases
- cerebral ischemia
- subarachnoid hemorrhage
- ischemia reperfusion injury
- signaling pathway
- blood brain barrier
- brain injury
- transcription factor
- pi k akt
- resting state
- white matter
- spinal cord injury
- oxidative stress
- functional connectivity
- heart failure
- traumatic brain injury
- acute myocardial infarction
- lipopolysaccharide induced
- inflammatory response
- coronary artery disease
- acute coronary syndrome