Inhibition of Anaplastic Lymphoma Kinase Protects From Ischemic Stroke.

Yue HuLuping ChangYuanbo ZhuXue GengZhongwang LiuRanran WangYiheng WangBing-Qiao ZhaoWenying Fan

Published in: Stroke (2024)

Our findings demonstrated that alectinib protects from stroke by regulating ischemic signaling cascades and suggest that ALK may be a novel therapeutic target for ischemic stroke.

Keyphrases

atrial fibrillation
diffuse large b cell lymphoma
cerebral ischemia
advanced non small cell lung cancer
ischemia reperfusion injury
tyrosine kinase
protein kinase
oxidative stress
subarachnoid hemorrhage