Lactone Derivatives Produced by a Phaeoacremonium sp., an Endophytic Fungus from Senna spectabilis.
Geraldo H SilvaMaria L ZeraikCamila M de OliveiraHelder L TelesHenrique C TrevisanLudwig H PfenningCamila P NicolliMaria C M YoungYvonne P MascarenhasLucas M AbreuAmanda C SaraivaAlexandra I MedeirosVanderlan da S BolzaniÂngela Regina AraújoPublished in: Journal of natural products (2017)
Three new isoaigialones, A, B, and C (1-3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained from the leaves of Senna spectabilis. The structures of these compounds were elucidated based on the analysis of spectroscopic data. Compounds 2 and 4 were active against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum. This is the first report of metabolites produced by an Phaeoacremonium sp., associated with S. spectabilis.