Intestinal tuft cells assemble a cytoskeletal superstructure composed of co-aligned actin bundles and microtubules.
Jennifer B SilvermanEvan E KrystofiakLeah R CaplanKen S LauMatthew J TyskaPublished in: bioRxiv : the preprint server for biology (2024)
This research leveraged advanced light and electron microscopy to perform quantitative morphometry of the intestinal tuft cell cytoskeleton. Three-dimensional reconstructions of segmented image data revealed a co-aligned actin-microtubule superstructure that may play a fundamental role in tuft cell function.
Keyphrases
- electron microscopy
- single cell
- induced apoptosis
- cell cycle arrest
- cell migration
- cell therapy
- deep learning
- electronic health record
- high resolution
- big data
- endoplasmic reticulum stress
- cell death
- magnetic resonance imaging
- machine learning
- mesenchymal stem cells
- image quality
- cell proliferation
- data analysis
- bone marrow
- contrast enhanced