Electric-field-induced coupling of aryl iodides with a nickel(0) complex.
Nicholas M OrchanianSophia GuizzoMichael L SteigerwaldColin P NuckollsLatha VenkataramanPublished in: Chemical communications (Cambridge, England) (2022)
The formation of carbon-carbon bonds with transition metal reagents serves as a cornerstone of organic synthesis. Here, we show that the reactivity of an otherwise kinetically inert transition metal complex can be induced by an external electric field to affect a coupling reaction. These results highlight the importance of electric field effects in reaction chemistry and offers a new strategy to modulate organometallic reactivity.