Induction of Melanoma Cell-Selective Apoptosis Using Anti-HER2 Antibody-Conjugated Gold Nanoparticles.

Hyeon Jun Jeon Byul Bo Ra Choi Kwang Ha Park Dae-Seok Hwang Uk-Kyu Kim Gyoo-Cheon Kim

Published in: Yonsei medical journal (2019)

GNP-HER2 can selectively kill G361 melanoma cells without affecting normal cells. The mechanism of G361 cell death upon treatment with GNP-HER2 was apoptosis accompanied by activation of caspases.

Keyphrases

cell cycle arrest
cell death
gold nanoparticles
pi k akt
induced apoptosis
endoplasmic reticulum stress
oxidative stress
single cell
cell therapy
signaling pathway
photodynamic therapy
cell proliferation
bone marrow
smoking cessation