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Association of genetic variation on X chromosome with systemic lupus erythematosus in both Thai and Chinese populations.

Pattarin TangtanatakulYao LeiKrisana JaiwanWanling YangManon BoonbangyangPunna KunhapanPimpayao SodsaiSurakameth MahasirimongkolPrapaporn PisitkunYi YangJakris Eu-AhsunthornwattanaWichai AekplakornNatini JinawathNareemarn NeelapaichitNattiya HirankarnYong-Fei Wang
Published in: Lupus science & medicine (2024)
Our study confirmed previous SLE associations in X chromosome, and identified two loci suggestively associated with SLE. More importantly, our study indicated a higher risk of SLE for females with trisomy X.
Keyphrases
  • systemic lupus erythematosus
  • disease activity
  • rheumatoid arthritis
  • copy number
  • dna methylation
  • genetic diversity