Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report).

Iryna O FedkoJouke-Jan HottengaQuinta HelmerHamdi MbarekFloris HuiderNajaf AminJoline W BeulensMarijke A BremmerPetra J EldersTessel E GaleslootLambertus A KiemeneyHanna M van LooH Susan J PicavetFemke RuttersAshley van der SpekAnne M van de WielCornelia van DuijnEco J C de GeusEdith J M FeskensCatharina A HartmanAlbertine J OldehinkelJan H SmitW M Monique VerschurenBrenda W J H PenninxDorret I BoomsmaMariska Bot

Published in: Psychological medicine (2020)

By assessing MDD status in the Netherlands using the LIDAS instrument, we were able to confirm previously reported MDD prevalence and heritability estimates, which suggests that this instrument can be used in epidemiological and genetic association studies of depression.

Keyphrases

depressive symptoms
major depressive disorder
sleep quality
genome wide
risk factors
gene expression
patient reported outcomes
bipolar disorder
case control