Gut microbiota and metabolites associate with outcomes of immune checkpoint inhibitor-treated unresectable hepatocellular carcinoma.
Pei-Chang LeeChi-Jung WuYa-Wen HungChieh Ju LeeChen-Ta ChiI-Cheng LeeKuo Yu-LunShih-Hsuan ChouJiing-Chyuan LuoMing-Chih HouYi-Hsiang HuangPublished in: Journal for immunotherapy of cancer (2022)
Fecal microbiota and bile acids were associated with outcomes of immunotherapy for uHCC. These findings highlight the potential role of gut microbiota and metabolites as biomarkers to predict outcomes of ICI-treated HCC.