Exploring the factors affecting classification and reporting of uncertain prenatal microarray findings, using a "virtual fetus" model-a pilot study.

Rachel Michaelson-CohenLiat Sheelo SalzerDana Brabbing-GoldsteinYuval YaronAdi RechesHagith YonathMiriam RegevHagit ShaniGheona AltarescuReeval SegelRivka Sukenik-HalevyHagit DaumTamar HarelVardiella MeinerLina Basel-SalmonSagi-Dain LenaIdit Maya

Published in: Prenatal diagnosis (2024)

Factors affecting CNV classification/reporting are mainly dosage, family phenotype, geneticist specialization and experience. Understanding factors from our pilot study may facilitate developing an algorithm for clinical consensus and optimal management.

Keyphrases

deep learning
machine learning
adverse drug
pregnant women
clinical practice
electronic health record