Heat shock protein 90 is downregulated in calcific aortic valve disease.
Jonna WeisellPauli OhukainenJuha NäpänkangasSteffen OhlmeierUlrich BergmannTuomas PeltonenPanu TaskinenHeikki RuskoahoJaana RysäPublished in: BMC cardiovascular disorders (2019)
We describe here a novel data set of proteomic changes associated with CAVD, including downregulation of the pro-inflammatory cytosolic protein, HSP90.
Keyphrases
- heat shock protein
- aortic valve
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- aortic valve replacement
- aortic stenosis
- heat shock
- electronic health record
- cell proliferation
- signaling pathway
- big data
- protein protein
- binding protein
- amino acid
- label free
- heart failure
- coronary artery disease
- small molecule
- artificial intelligence
- deep learning
- ejection fraction
- innate immune