Selinexor in Combination with R-CHOP for Frontline Treatment of Non-Hodgkin Lymphoma: Results of a Phase I Study.
Erlene K SeymourHusain Yar KhanYiwei LiMahmoud ChakerIrfana MuqbilAmro AboukameelRadhakrishanan RamchandrenChristiane HoudeGolbon SterbisJay YangDivaya BhutaniSilvana PregjaKathy ReichelAmy HuddlestunColleen NeveuxKelly CoronaYosef LandesmanJatin ShahMichael KauffmanSharon ShachamRamzi M MohammadAsfar S AzmiJeffrey A ZonderPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
SINE compounds enhance the activity of CHO in vitro and in vivo. Selinexor in combination with R-CHOP was generally well tolerated and showed encouraging efficacy in NHL (NCT03147885).
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