Progression of Type 1 Diabetes: Circulating MicroRNA Expression Profiles Changes from Preclinical to Overt Disease.

Aritania Sousa Santos Ludmila Rodrigues Pinto Ferreira Amanda Cabral da Silva Laís Isidoro Alves Jullian Gabriel Damasceno Leslie Domenici Kulikowski Edécio Cunha-Neto Maria Elizabeth Rossi da Silva

Published in: Journal of immunology research (2022)

Our data suggests a potential influence of DEMs on disease progression from the initial autoimmune lesion up to severe beta cell dysfunction and the role of miRNAs hsa-miR-16 and hsa-miR-200a-3p as biomarkers of T1D progression.

Keyphrases

type diabetes
cell therapy
cell proliferation
long non coding rna
single cell
multiple sclerosis
electronic health record
cardiovascular disease
long noncoding rna
early onset
glycemic control
big data
mesenchymal stem cells
human health
metabolic syndrome
bone marrow
deep learning
weight loss