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Phylogenomics of Leptospira santarosai, a prevalent pathogenic species in the Americas.

Diana ChinchillaCecilia NievesRicardo GutiérrezVallier SordoilletFrédéric J VeyrierMathieu Picardeau
Published in: PLoS neglected tropical diseases (2023)
In conclusion, we report a comprehensive genome analysis of pathogenic Leptospira species with a focus on L. santarosai. Our study sheds new light onto the genomic diversity, evolutionary history, and epidemiology of leptospirosis in America and globally. Our findings also expand our knowledge of the genes driving O-antigen diversity. In addition, our work provides a framework for understanding the virulence and spread of L. santarosai and for improving its surveillance in both humans and animals.
Keyphrases
  • genome wide
  • escherichia coli
  • healthcare
  • pseudomonas aeruginosa
  • staphylococcus aureus
  • copy number
  • risk factors
  • genetic diversity
  • cystic fibrosis
  • candida albicans
  • genome wide analysis