Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study.
Vito LampasonaMassimiliano SecchiMarina ScaviniElena BazzigaluppiCristina BrigattiIlaria MarzinottoAlberto DavalliAmelia CarettoAndrea LaurenziSabina MartinenghiChiara MolinariGiordano VitaliLuigi Di FilippoAlessia MercalliRaffaella MelziCristina TresoldiPatrizia Rovere QueriniGiovanni LandoniFabio CiceriEmanuele BosiLorenzo PiemontiPublished in: Diabetologia (2020)
The observed increased severity and mortality risk of COVID-19 pneumonia in patients with hyperglycaemia was not the result of an impaired humoral response against SARS-CoV-2. RBD IgG positivity was associated with a remarkable protective effect, allowing for a cautious optimism about the efficacy of future vaccines against SARs-COV-2 in people with diabetes. Graphical abstract.