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Relative Wash-In Rate in Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a New Prognostic Biomarker for Event-Free Survival in 82 Patients with Osteosarcoma: A Multicenter Study.

Gijsbert M KalisvaartRichard E EvenhuisWillem GrootjansThomas Van Den BergheMartijn CallensJudith V M G BovéeDavid CreytensAndré B P van KuilenburgFrank M SpeetjensLore LapeireGwen M L SysMarta FioccoKoenraad L VerstraeteMichiel Adreanus van de SandeJohan L Bloem
Published in: Cancers (2024)
The predicted poor chemo response with MRI (rWIR < 2.3) is associated with shorter EFS even when adjusted for known clinical covariates and shows similar results to histological response evaluation. rWIR is a potential tool for future response-based individualized healthcare in osteosarcoma patients before surgical resection.
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