Circulating microRNAs as biomarkers of radiation-induced cardiac toxicity in non-small-cell lung cancer.
Peter G HawkinsYilun SunRobert T DessWilliam C JacksonGrace SunNan BiMuneesh TewariJames A HaymanGregory P KalemkerianShirish M GadgeelTheodore S LawrenceRandall K Ten HakenMartha M MatuszakFeng-Ming Spring KongMatthew J SchipperShruti JollyPublished in: Journal of cancer research and clinical oncology (2019)
We identified a pre-treatment c-miRNA signature prognostic for G3 + RICT. With further development, pre- and mid-treatment c-miRNA profiling could contribute to patient-specific dose selection and treatment adaptation.