Assessment of Chemotherapy-Induced Organ Damage with Ga-68 Labeled Duramycin.
Anne RixNatascha Ingrid DrudeAnna MrugallaFerhan BaskayaKoon Yan PakBrian GrayHans-Jürgen KaiserRené Hany TolbaEva FiegleWiltrud LederleFelix Manuel MottaghyFabian KießlingPublished in: Molecular imaging and biology (2021)
[68Ga]NODAGA-duramycin PET/CT was successfully applied to non-invasively detect chemotherapy-induced organ toxicity with high sensitivity in mice. It, therefore, represents a promising alternative to standard toxicological analyses with a high translational potential.