Esophageal Dilation and Other Clinical Factors Associated With Pulmonary Function Decline in Patients With Systemic Sclerosis.
Kimberly S LakinAileen HoffmannCarrie RichardsonDavid AabyJungwha LeeJane DematteRishi AgrawalHatice SavasXiaoping WuRowland W ChangMonique E HinchcliffPublished in: The Journal of rheumatology (2021)
In patients with SSc, Scl-70 positivity is a risk factor for FVC% predicted decline at 5 years. Esophageal dilation on HRCT was associated with a minimal, nonclinically significant decline in DLCO and no change in FVC during the 5-year follow-up. These results have prognostic implications for SSc-ILD patients with esophageal dilation.