Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis.
Ashok AgarwalRossella CannarellaRamadan SalehFlorence BoitrelleMurat GulTuncay ToprakGianmaria SalvioMohamed ArafaGiorgio Ivan RussoAhmed M HarrazRajender SinghNicolás GarridoTaha Abo-Almagd Abdel-Meguid HamodaAmarnath RambhatlaParviz K KavoussiShinnosuke KurodaGökhan ÇalıkPallavi SainiErman CeyhanFotios DimitriadisRalf Reinhold HenkelAndrea CrafaAyad PalaniMesut Berkan DuranEvangelos MaziotisEmine Saïs-HamzaMarion BendayanMahsa DarbandiTan V LeSezgin GüneşPetroula A TsioulouPallav SenguptaBerk HazirGökhan ÇekerSara DarbandiDamayanthi DurairajanayagamAzin AghamajidiNoora AlkhalidiEmrullah SogutdelenKristian LeisegangAbdullah AlfakhriChristopher Chee Kong HoVineet MalhotraFederica FinocchiLuís CrisóstomoRaghavender KosgiHaitham ElBardisiArmand ZiniPonco BirowoGiovanni M Colpi ForumHyun Jun ParkEge Can ŞerefoğluVinh Nguyen QuangEdmund Y KoJean J M C H de la RosetteGermar-Michael PinggeraNguyen Ho Vinh PhuocHussein KandilRupin ShahPublished in: The world journal of men's health (2022)
This study provides a high level of evidence in favor of a positive effect of VR to improve conventional semen parameters in infertile men with clinical varicocele. To the best of our knowledge, this is the first SRMA to compare changes in conventional semen parameters after VR with changes in parameters of a control group over the same period. This is in contrast to other SRMAs which have compared semen parameters before and after VR, without reference to a control group. Our findings strengthen the available evidence and have a potential to upgrade professional societies' practice recommendations favoring VR to improve conventional semen parameters in infertile men.