Cerebrospinal fluid neurofilament light chain differentiates primary psychiatric disorders from rapidly progressive, Alzheimer's disease and frontotemporal disorders in clinical settings.
Dhamidhu EratneSamantha M LoiQiao-Xin LiChristiane StehmannCharles B MalpasAlexander SantilloShorena JanelidzeClaire CadwalladerNirbaanjot WaliaBlair NeyVictoria LewisMatteo SenesiChristopher FowlerAmelia McGladeShiji VargheseParsa RavanfarWendy KelsoSarah FarrandMichael KeemMatthew KangAnita M Y GohKunal DhimanVeer GuptaRosie WatsonNawaf YassiCath Kaylor-HughesRichard KanaanPiero PeruccaHannah DobsonLucy VivashRashida AliTerence J O'BrienOskar HanssonHenrik ZetterbergKaj BlennowMark WalterfangColin L MastersSamuel F BerkovicSteven CollinsDennis Velakoulisnull nullPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2022)
We demonstrated strong generalizable evidence for the diagnostic utility of CSF NfL in differentiating ND from psychiatric disorders, with high accuracy.