Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System-A Case Report.
Hrvoje JakovacAntun FerenčićChristophe StembergerBojana Mohar VitezićDražen CuculićPublished in: Tropical medicine and infectious disease (2022)
Mounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio pathological substrates of COVID-related arrhythmias have not been clarified yet. Here, we report findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens and genes in the atrioventricular node (AV-node) of a cardiac conduction system, pointing to its direct infection as a possible arrhythmogenic factor.
Keyphrases
- respiratory syndrome coronavirus
- sars cov
- coronavirus disease
- lymph node
- left ventricular
- dendritic cells
- genome wide
- physical activity
- loop mediated isothermal amplification
- community dwelling
- heart failure
- gene expression
- real time pcr
- dna methylation
- label free
- transcription factor
- atrial fibrillation
- sensitive detection