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Raised Serum Markers of T Cell Activation and Exhaustion in Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency.

Mai Sasaki Aanensen FrazAnnika Elisabet MichelsenNatasha MoeTrond Mogens AaløkkenMagnhild Eide MacphersonIngvild NordøyPål AukrustEli TaraldsrudAre Martin HolmThor UelandSilje Fjellgård JørgensenBørre Fevang
Published in: Journal of clinical immunology (2022)
GLILD patients have elevated serum markers of T cell activation and exhaustion, pulmonary epithelium injury, and ECM remodeling, pointing to potentially important pathways in GLILD pathogenesis, novel targets for therapy, and promising biomarkers for clinical evaluation of these patients.
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