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Mining the deep Red-Sea brine pool microbial community for anticancer therapeutics.

Luke EsauGuishan ZhangSunil SagarUlrich StinglVladimir B BajicMandeep Kaur
Published in: BMC complementary and alternative medicine (2019)
In this study, we identified several extracts able to induce caspase-dependent apoptosis in various cancer cell lines. Further investigations and isolation of the active compounds of these Red Sea brine pool microbes may offer a chemotherapeutic potential for cancers with limited treatment options.
Keyphrases
  • microbial community
  • cell death
  • antibiotic resistance genes
  • papillary thyroid
  • oxidative stress
  • endoplasmic reticulum stress
  • small molecule
  • induced apoptosis
  • squamous cell carcinoma
  • risk assessment
  • young adults