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Sequential transplantation of the liver-kidney-heart from different donors: a case report.

Liaoran WangYu ZhangHang YuJiang-Ping SongYi Wang
Published in: European heart journal. Case reports (2023)
The presented case exemplifies the potential and feasibility of sequential multi-organ transplantation. The multifaceted interplay between the transplanted organs and the immunosuppressive pharmaceuticals likely exert distinct influences on transplantation immune regulation, possibly diverging from the dynamics observed in single-organ transplantation. A comprehensive exploration of the mechanisms governing immune responses in the context of multi-organ transplantation could yield valuable insights for mitigating graft dysfunction. Furthermore, the rapid progression of atherosclerosis observed after liver and kidney transplantation necessitates further scrutiny to elucidate potential correlations with the post-transplantation state.
Keyphrases
  • kidney transplantation
  • cell therapy
  • immune response
  • cardiovascular disease
  • heart failure
  • type diabetes
  • mesenchymal stem cells
  • risk assessment
  • inflammatory response