Tubulo-interstitial inflammation increases the risk of graft loss after the recurrence of IgA nephropathy.
Emilio Rodrigo-CalabiaLuis F QuintanaTeresa Vázquez-SánchezAna I Sánchez-FructuosoAnna BuxedaEva GavelaJuan M CazorlaSheila CabelloIsabel BeneytoMaría-Ovidia López OlivaFritz DiekmannJosé M Gómez-OrtegaNatividad C RomeroMaría José Pérez-SáezAsunción SanchoAuxiliadora MazuecosJordi Espí-ReigCarlos JiménezDomingo HernándezPublished in: Clinical kidney journal (2023)
In kidney transplant recipients with IgAN recurrence, TII contributes to increasing the risk of CKD5/DCGL independently of previously well-known variables. We suggest adding TII along with the Oxford classification to the clinical variables to identify recurrent IgAN patients at increased risk of graft loss who might benefit from intensified immunosuppression or specific IgAN therapies.