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The natural compound obtusaquinone targets pediatric high-grade gliomas through ROS-mediated ER stress.

Jian TengGhazal LashgariElie I TabetBakhos A Tannous
Published in: Neuro-oncology advances (2020)
Our data demonstrate the utility and feasibility of OBT as a potential therapeutic option for improving the clinical treatment of pHGGs.
Keyphrases
  • high grade
  • low grade
  • dna damage
  • cell death
  • electronic health record
  • reactive oxygen species
  • big data
  • combination therapy
  • oxidative stress
  • young adults
  • machine learning
  • data analysis
  • replacement therapy