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Reversible renal-limited thrombotic microangiopathy due to gemcitabine-dexamethasone-cisplatin therapy: a case report.

Masashi NishikuboYoshimitsu ShimomuraNobuhiro HiramotoNaohiko SawamuraTakako YamaguchiShigeo HaraTakayuki Ishikawa
Published in: BMC nephrology (2021)
Drug-induced TMA occurs early after gemcitabine and cisplatin use in renal-limited form and is reversible when detected and managed in a timely manner. Urinalysis, which is simple and inexpensive and can be easily performed, is a beneficial screening tool for early-onset drug-induced TMA among patients who receive gemcitabine-dexamethasone-cisplatin therapy.
Keyphrases
  • drug induced
  • liver injury
  • early onset
  • late onset
  • locally advanced
  • low dose
  • high dose
  • adverse drug
  • squamous cell carcinoma
  • rectal cancer
  • stem cells