The Role of Left-Atrial Mechanics Assessed by Two-Dimensional Speckle-Tracking Echocardiography to Differentiate Hypertrophic Cardiomyopathy from Hypertensive Left-Ventricular Hypertrophy.
Nicoleta-Monica Popa-FoteaMiruna Mihaela MicheuNicoleta OprescuAdriana AlexandrescuMaria GreavuSebastian OnciulRoxana OnutIoana PetreAlina Ioana ScărlătescuMonica StoianRazvan TiculescuDiana ZamfirMaria DorobanțuPublished in: Diagnostics (Basel, Switzerland) (2021)
LA reservoir, conduit, and pump functions are decreased in HCM compared to HTN patients with similar LVH. We report the ratios between LA contraction S/SR and IVS thickness as novel parameters with high accuracy in discriminating LVH due to HCM. The presence of P/LP variants in sarcomeric or sarcomeric-associated genes could be associated with more severe LA dysfunction.
Keyphrases
- hypertrophic cardiomyopathy
- left ventricular
- left atrial
- mitral valve
- cardiac resynchronization therapy
- acute myocardial infarction
- heart failure
- aortic stenosis
- blood pressure
- genome wide
- optical coherence tomography
- early onset
- atrial fibrillation
- bioinformatics analysis
- gene expression
- aortic valve
- coronary artery disease
- water quality
- pulmonary hypertension