Impact of GeneXpert MTB/RIF® on treatment initiation and outcomes of RIF-resistant and RIF-susceptible TB patients in Vladimir TB dispensary, Russia.
Julia V ErshovaGrigory V VolchenkovTatiana R SomovaTatiana A KuznetsovaNatalia V KaunetisDorothy KaminskiOlga V DemikhovaLarisa N ChernousovaIrina A VasilyevaEleanor M KerrJ Peter CegielskiEkaterina V KurbatovaPublished in: BMC infectious diseases (2020)
We observed that availability of Xpert for initial diagnosis significantly reduced the time to SLD treatment for RIF-resistant patients in the Vladimir TB Dispensary. Although implementation of rapid diagnostics did not improve treatment outcomes, early diagnosis of MDR-TB is important for selection of appropriate treatment regimen and prevention of transmission of drug-resistant strains of TB.
Keyphrases
- mycobacterium tuberculosis
- drug resistant
- pulmonary tuberculosis
- end stage renal disease
- ejection fraction
- multidrug resistant
- newly diagnosed
- peritoneal dialysis
- healthcare
- escherichia coli
- prognostic factors
- primary care
- type diabetes
- metabolic syndrome
- acinetobacter baumannii
- cystic fibrosis
- skeletal muscle
- quality improvement