Immune characterization of the HBHA-specific response in Mycobacterium tuberculosis-infected patients with or without HIV infection.

Teresa ChiacchioGiovanni DeloguValentina VaniniGilda CuzziFlavio De MaioCarmela PinnettiAlessandro SampaolesiAndrea AntinoriDelia Goletti

Published in: PloS one (2017)

These results characterize the impact of HIV infection in CD4- and CD8-specific response to HBHA in both LTBI and TB patients. HIV infection impairs the CD4 response to HBHA and likely this may lead to an impairment of TB control.

Keyphrases

mycobacterium tuberculosis
antiretroviral therapy
end stage renal disease
ejection fraction
chronic kidney disease
nk cells
newly diagnosed
pulmonary tuberculosis
peritoneal dialysis