Predictability and stability testing to assess clinical decision instrument performance for children after blunt torso trauma.
Aaron E KornblithChandan SinghGabriel DevlinNewton AddoChristian J StreckJames F HolmesNathan KuppermannJacqueline Grupp-PhelanJeffrey FinemanAtul J ButteBin YuPublished in: PLOS digital health (2022)
The PCS data science framework vetted the PECARN CDI and its constituent predictor variables prior to external validation. We found that the 3 stable predictor variables represented all of the PECARN CDI's predictive performance on independent external validation. The PCS framework offers a less resource-intensive method than prospective validation to vet CDIs before external validation. We also found that the PECARN CDI will generalize well to new populations and should be prospectively externally validated. The PCS framework offers a potential strategy to increase the chance of a successful (costly) prospective validation.