A Rare Case of a Transgender Female With Breast Implant-Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature.
Naba AliKunal K SindhuRichard L BakstPublished in: Journal of investigative medicine high impact case reports (2020)
We are reporting a case of a 54-year-old transgender female with a history of breast augmentation with bilateral silicone implants. Seventeen years later, she presented with an enlarging right breast mass. Pathology confirmed breast implant-associated anaplastic large cell lymphoma (Ann Arbor Stage IIE, TNM Stage III BIA-ALCL). The patient underwent bilateral capsulectomy, sentinel lymph node biopsy with adjuvant CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy, and radiotherapy to the right chest, axilla, and supraclavicular lymph nodes. BIA-ALCL is a rare entity, especially in transgender females. We report this case and a review of the literature in this report.
Keyphrases
- sentinel lymph node
- early stage
- lymph node
- rare case
- diffuse large b cell lymphoma
- locally advanced
- soft tissue
- single cell
- case report
- neoadjuvant chemotherapy
- radiation therapy
- cell therapy
- radiation induced
- low dose
- drug delivery
- stem cells
- emergency department
- adverse drug
- hepatitis c virus
- cancer therapy
- drug induced