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Green Liquid Chromatography Method for the Determination of Related Substances Present in Olopatadine HCl Nasal Spray Formulation, Robustness by Design Expert.

Leela Prasad KowtharapuNaresh Kumar KatariChristian A SandovalSiva Krishna MuchakayalaVijay Kumar Rekulapally
Published in: Journal of AOAC International (2022)
The proposed method is QbD utilized and green chemistry assessed impurities determination method for OPT in nasal spray formulation.
Keyphrases
  • liquid chromatography
  • solid phase extraction
  • drug delivery
  • mass spectrometry
  • molecularly imprinted
  • high resolution mass spectrometry
  • high resolution
  • drug discovery