Neurodevelopmental consequences of preterm punctate white matter lesions: a systematic review.

Clara Adriana Maria de BruijnStefano Di MicheleMaria Luisa TatarannoLuca Antonio RamenghiAndrea RossiMariya MalovaManon BendersAgnes van den HoogenJeroen Dudink

Published in: Pediatric research (2022)

PWML is common in preterm infants and seems predictive of adverse NDO. DWI and SWI MRI sequences are informative because the different patterns suggest a difference in the underlying pathology. The type and severity of impairments are related to the number and location of PMWL. Our review can inform clinicians and parents about the NDO of preterm infants with a diagnosis of PWML. Prospective neuroimaging case-control cohort studies are recommended.

Keyphrases

preterm infants
low birth weight
case control
white matter
diffusion weighted imaging
contrast enhanced
magnetic resonance imaging
diffusion weighted
multiple sclerosis
preterm birth
computed tomography
emergency department
congenital heart disease